Regenerative medicine, held over years.
Your body rebuilds itself constantly. The work is keeping repair ahead of breakdown — measured, physician-directed, and reviewed every year.
Four levels of access
What separates them is not how much medicine you get. It is how directly and how quickly you can reach him. Seats are capped above the entry tier.
Signal
$10,000per yearA scheduled results review. Dr. Sethuraman personally reviews and signs every interpretation.
- The full diagnostic battery — metabolic, hormonal, cardiovascular, gut, toxin
- Body composition, metabolic testing, annual EKG
- Two 60-minute results consultations
- A written annual blueprint
- Member pricing on everything else
No therapies included — no hormone therapy, peptides, physical therapy or after-hours access.
Resonance
$30,000per yearA direct line during business hours, answered same or next day. Four physician visits a year.
- Everything in Signal, with gut and hormone work upgraded
- Complete hormone therapy, medications included
- Physician-directed peptide therapy at practice cost, plus a $2,500 credit
- 12 physical therapy visits, 12 Omni-wave, 36 recovery services
- Whole-body MRI every two years · no scheduling waitlist
Advanced cardiac imaging and multi-cancer detection sit at the next level.
Amplitude
$95,000per yearHis personal mobile. A response within 24 hours, seven days a week. Quarterly visits plus unlimited interval consults.
- Everything in Resonance
- Coronary CT with flow analysis, whole-body MRI and multi-cancer detection, annually
- Unlimited physician-directed peptide therapy within the SPI formulary, PT, recovery and HBOT
- $7,500 annual credit
- Medical advocacy — hospitalisations coordinated, outside imaging reviewed
- Spouse enrolled at Resonance, half price
Family beyond a spouse, in-home services and an included procedure sit at the tier above.
Sovereign
$250,000per yearUnrestricted access, 24/7/365, anywhere in the world. He answers — no triage, no covering physician.
- Everything in Amplitude
- One major regenerative procedure a year, at physician discretion
- Home red-light therapy bed, delivered and installed
- Spouse and dependents at full Resonance benefits
- An annual two-day onsite intensive — full re-baselining
- In-home draws, IV and diagnostics · travel medicine · surgical concierge
- $20,000 annual credit
Reviewed and renewed each year by mutual agreement. Seats release in waitlist order.
See the full comparison
| Signal | Resonance | Amplitude | Sovereign | |
|---|---|---|---|---|
| How you reach him | Scheduled review | Direct line, business hours | Personal mobile, 24 hr | 24/7/365, worldwide |
| Physician visits | 2 results consults | 4 per year | Quarterly + unlimited interval | Unrestricted |
| Membership cap | None | 150 | 40 | 10 seats |
| Healthspan, hormone & cardiovascular panels | Included | Included | Included | Included |
| Gut analysis | Gut Zoomer | GI Effects + Microbiomix | GI Effects + Microbiomix | Semi-annual GI Effects |
| Bio-Well & GlycoCheck | Twice yearly | Quarterly | Unlimited | Unlimited |
| Written annual blueprint | Included | Included | Included | Rebuilt at the annual intensive |
| Hormone therapy, incl. medication | — | Included | Included | Included |
| Physician-directed peptide therapy | — | At practice cost | Unlimited within formulary | Unlimited within formulary |
| Annual credit | — | $2,500 | $7,500 | $20,000 |
| Physical therapy | — | 12 visits | Unlimited | Unlimited |
| Recovery suite & Omni-wave | — | 12 + 36 services | Unlimited, incl. HBOT | Unlimited, incl. HBOT |
| Whole-body MRI | — | Every 2 years | Annually | Annually |
| Coronary CT with flow analysis | — | — | Annually | Annually |
| Multi-cancer blood detection | — | — | Annually | Annually |
| Medical advocacy | — | — | Included | Included |
| Surgical scheduling | — | No waitlist | Priority | Full surgical concierge |
| Family | — | — | Spouse at Resonance, half price | Spouse & dependents |
| Home red-light bed | 10% member price | 20% member price | 40% member price | Included, installed |
| Major regenerative procedure | — | — | — | One per year |
| Annual two-day onsite intensive | — | — | — | Included |
| In-home draws, IV & diagnostics | — | — | — | Included |
| Travel medicine & global referral | — | — | — | Included |
Advanced imaging and blood-based detection are used to track you against yourself over time, not as population screening. Peptide therapy inside a membership is still physician-directed and limited to the SPI formulary.
The order we work in
Most plans fail because they start by adding. Peptides, hormones and light are late steps.
Subtract
Sleep debt, uncontrolled blood sugar, chronic inflammation, deconditioning.
Add
Strength, protein, movement, recovery — dosed so you could hold it on a bad week.
Build coherence
Make the pieces work together instead of against each other.
Strengthen adaptation
Only now do targeted regenerative therapies earn their place.
Membership also changes what everything else costs
| Home red-light bed | Regenerative procedures | Transcendence Clinics | |
|---|---|---|---|
| Signal | 10% member price | 10% off · member consult rate | 10% off |
| Resonance | 20% member price | 15% off · candidacy workup included | 20% off |
| Amplitude | 40% member price | 30% off · priority, no waitlist | 30–50% off |
| Sovereign | Included, delivered & installed | 50% off, plus one procedure yearly | Executive programme included |
Peptide therapy on its own
Included from Resonance upward. Available separately only after an evaluation, and only when a protocol is appropriate.
A consultation, $150
A physician decides whether peptide therapy is appropriate. Often it is not. If it is, the $150 is credited toward your first month.
A protocol, if warranted
Matched to a goal and to your evaluation, from the SPI formulary, directed by the practice.
Monthly, while appropriate
Reviewed on an ongoing basis. Not a standing order you renew forever without being seen.
What monthly direction costs, once you have been seen
Essential — $99/month
One physician-directed protocol matched to your goal. Monthly delivery, free shipping.
Plus — $249/month
Two stacked protocols plus a longevity addition. Priority fulfilment.
Vital — $499/month
Full-spectrum, multi-system protocols with concierge support.
No peptide is named, dosed or priced anywhere on this site, and the prices sit behind the consultation on purpose.
Enrolment terms
- Term
- Annual. Paid in full at enrolment, or twelve monthly instalments with a 4% administrative premium.
- Refunds
- Non-refundable after the first thirty days.
- Insurance
- Private pay only. Membership is not insurance and is never billed to it.
- Included services
- Non-transferable. Unused credits expire at the end of the membership year.
- Seats
- Amplitude and Sovereign seats release in waitlist order.
Membership starts with a conversation, not a checkout page.
If you have a spine problem right now, book a consultation instead.